Facilities

The Centenary Institute houses world class facilities which are crucial for our scientists to undertake their groundbreaking research.

The Centenary Institute houses a PC3 containment facility, the only one in Australia which permits work with experimental tuberculosis infection. This facility is essential for our ongoing investigations examining the immunological and inflammatory response stimulated by Mycobacterium tuberculosis infection and the genetic factors that control resistance and susceptibility to tuberculosis.

The facility contains equipment permitting cell culture, genetic manipulation of bacteria and aerosol exposure system for animal infection models.

The Microinjection Facility allows for the use and development of the latest transgenic (over expression of a single gene) and knockout (deletion of a single gene) technology (collectively called genetically modified) has for many years been a high priority for Centenary. Our facility is the longest established in the state and one of the most productive in Australia in terms of numbers of mouse strains produced. Centenary's transgenic and knockout mice are the subject of hundreds of scientific publications.

Genetically modified mouse lines are bred under Level 2 Specific Pathogen Free conditions in the Centenary Institute Animal Facility. Climate control, strict hygiene and sterilisation procedures, the provision of quality irradiated feed and environmental enrichment provide an optimal environment for the mice. The PC2 approved facility offers differing levels of containment with dedicated areas for immunodeficient mice, infectious studies and quarantine. The facility is an Australian Quarantine approved premise.

The Centenary Institute also maintains a state-of-the art Cytometry and Imaging facility. For more information on this, click here.