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Centenary Institute - Medical Research

Breakthroughs at Centenary Institute

As a world-leading independent Medical Research Institute Centenary’s vision is to improve human health through excellence in medical research.

Since our inception over three decades ago, our researchers have contributed to life-changing scientific advances in the areas of cancer, inflammation and cardiovascular diseases.

These breakthroughs highlighted below show how our researchers are better understanding diseases, to ultimately find treatments and cures, ensuring that people can live healthier and longer lives.

Visit our Media Centre for information on all our discoveries and scientific advances.

Click below to see our breakthroughs by year

 
 

2020

  • Discovered a potential new therapy for cerebral cavernous malformations (CCMs), a devastating disease that can result in stroke and seizures. >> More
  • Developed a new therapeutic strategy that could potentially help in the fight against advanced-stage melanoma. >> More
  • Discovered that tumour-resident T cells are a critical determinant in survival rates of patients suffering from throat cancer. >> More

 

 

2019

  • Found that an Australian sea sponge could hold the key to successfully combatting the deadly disease tuberculosis. >> More
  • Uncovered the impact of new technology on the over-diagnosis of a little known inherited heart disease. >> More
  • Discovered a key reason why the influenza virus is so effective at establishing infection and causing damage in the lungs. >> More
  • Developed and tested a new type of vaccine targeting tuberculosis, the world’s top infectious disease killer. >> More
  • Discovered that aspirin could be used to treat patients with severe tuberculosis infection. >> More
 

2018

  • Improved the diagnosis rate of a potentially deadly heart condition by up to 20 per cent. >> More
  • Determined how to develop safer blood-clotting drugs. >> More
  • Developed a novel drug which could potentially be used to treat patients with diabetic retinopathy; the main cause of blindness from diabetes. >> More
  • Discovered a cure for a sub-set of one of the most common genetic blood diseases in the world, Beta-thalassemia. >> More
  • Developed a novel drug which is being touted as a major step forward in the battle against obesity. >> More
  • Created a more realistic model of primary liver cancer. >> More
  • Discovered a potential new pathway for cancer therapies. >>More
 

2017

  • Developed a new drug that could be effective in some of the hardest to treat cancers such as pancreatic and liver cancer. >> More
  • Discovered that gut bacteria could hold the key to treating and preventing potentially deadly strokes. >> More
  • Discovered a new cell in the liver, which will inform future investigations into liver disease and liver cancer. >> More
  • Identified antibacterial compounds in soil that could lead to new treatments for tuberculosis. >> More
  • Discovered a common pattern in the process of gene regulation that could be the key to treating and finding cures for cancers and other diseases. >> More
  • Revealed that a naturally occurring chemical process to DNA can change the way information in genes are read to help treat cancer. >> More
 

2016

  • Revealed new genetic insights on causes of sudden cardiac death in the young. >> More
  • Identified the first possible link between the heart and the brain in epilepsy patients. >> More
  • Identified drug targets for cerebral cavernous malformations. >> More
  • Revealed new information about the way the cornea responds to damage to assist in treating blindness. >> More
 
 
 
 

2015

  • Discovered that an enzyme could be a potential therapeutic target for limiting tumour growth and its spread into the liver. >> More
  • Discovered new links between nutrition and prostate cancer. >> More
 
 
 
 
 
 
 

2013

  • Discovered a new immune cell type that causes skin diseases and skin allergies.
 
 
 
 
 
 
 
 
 

2012

  • Discovered new drug candidates for prostate and breast cancer.
 
 
 
 
 
 
 
 
 

2011

  • Developed an integrated genetic and clinical approach for early diagnosis and treatment solutions to prevent sudden cardiac death.
  • Discovery of a new mechanism by which the liver kills immune cells responsible for graft rejection and viral clearance.
 
 
 
 
 
 
 

2009

  • Discovered micro RNA can be used to treat diseases associated with vascular leak eg stroke and myocardinal infarction.
 
 
 
 
 
 
 
 

2005

  • Discovered anti TNF therapy increases the risk of reactivation of Tuberculosis.
  • Improved the identification of human regulatory T Cells, a discovery used widely in clinical research settings.
 
 
 
 
 
 
 
 

1989

  • Discovered critical insights into the role of the immune system in health and disease.