Patrick Bertolino leads the Liver Immunology Group and has been a Faculty member at the Centenary Institute since 2011. He is considered one of the leading experts in Liver Immunology internationally, and is acknowledged as the leader in this field in Australia, where he drives the main group working in this new and expanding discipline.
Patrick Bertolino has worked in the same field for the last 20 years in excellent research institutes, and has been trained by first class immunologists (ENS-Lyon, France: Chantal Rabourdin-Combe; WEHI: Jacques Miller; Centenary Institute: Barbara Fazekas de St Groth). During this time, he has developed unique transgenic mouse models and has acquired a leading international reputation in liver immunology. This reputation derives from original landmark pioneering papers that have transformed the field, and are now part of current paradigms. These include the first demonstration of naïve CD8 T cell activation in the liver, the first evidence of direct interaction between circulating T cells and hepatocytes, the role of intrahepatic T cell activation in tolerance, and the discovery that liver-activated T cells are deleted in the lysosomes of hepatocyte.
Patrick Bertolino has had consistent success in obtaining major international and national project grants as CIA, demonstrating independence and leadership. He has held continuous NHMRC funding since 2000: 2 Program Grants (PI 2005-9, CI 2010-4), and 6 Project grants (5 CIA, 1 CIB). He has also obtained highly competitive international funding (Roche Solid Organ Transplantation Research Foundation).
Learn more about his Research Program.