Lipid metabolism and lipid signalling molecules are excellent targets for therapeutic intervention, as evident in the fact that many of the most successful therapeutics target lipid metabolism, e.g. statins, non-steroidal anti-inflammatory drugs, and Fingolimod (used to treat multiple sclerosis).
Highlights of our recent research include (1) Identifying the sphingosine 1-phosphate receptors as a good target for new Alzheimer’s Disease therapeutics; and (2) Developing the world’s first potent and specific inhibitor of the enzyme ceramide synthase 1, which we have used to demonstrate a major role for this enzyme in the control of fat storage vs its use as an energy source.
Associate Professor Anthony Don, Sydney Medical School
Phone: (02) 8627 5578
PhD, University of New South Wales, Sydney, 2004
Postdoctoral Fellow, Scripps Research Institute, USA, 2004-2008
Research Fellow, University of New South Wales, Sydney, 2009-2012
Senior Research Fellow, University of New South Wales, Sydney, 2013-2016
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- Tim Couttas, Research Fellow
- Laura Hunter, Research Assistant
- Mona Lei, PhD student
- Collin Tran, PhD student
- Ameline Lim, PhD student