Professor Julian Paton
Professor, Faculty of Medical and Health Science University of Auckland
The presentation will demonstrate how physiological findings are being harnessed to drive novel pre-clinical and clinical studies to treat hypertension and heart failure. Work on purinergic transmission within the carotid body and how this may offer novel treatment of excessive sympathetic activity, hypertension and breathing disorders will be described. Regarding heart failure, the effectiveness of a new form of cardiac pacing using an analogue device that re-instates respiratory sinus arrhythmia will be demonstrated.
Julian Paton is an integrative physiologist with research interests in the autonomic regulation of cardiovascular system function, reflex regulation of sympathetic and parasympathetic motor outflows and the neural coupling between cardiovascular and respiratory systems in health and disease. He is identifying novel ways to alleviate symptoms of hypertension and heart failure using pre-clinical animal models (small and large) and translating this work to humans by performing first-in-man proof of principle studies. His work involves both surgical intervention, building and testing novel medical devices, and using repurposed small molecules. He has won a number of international prizes for his work, has published >380 papers and has an h index of 65.
Read more about Professor Julian Paton’s work here.
Download the poster here.