Associate Professor Kaylene Young
Theme Leader for Brain Health and Disease Research, Menzies Institute for Medical Research, University of Tasmania
Oligodendrocyte progenitor cells (OPCs) comprise the largest proliferating cell population in the adult brain. They divide to produce new oligodendrocytes throughout life – a function that allows them to contribute to learning and memory processes and enhance remyelination in response to a demyelinating injury. However, the dysregulation of OPC proliferation has also been associated with the formation of paediatric and adult glioma. This presentation explores the key regulators that determine whether OPC behaviour will help or hinder brain function.
A/Prof Kaylene Young is the Inaugural Macquarie Group Foundation – MS Research Australia Fellow and Theme Leader for Brain Health and Disease Research at the Menzies Institute for Medical Research, the University of Tasmania. Across her career, Kaylene has studied neural stem and progenitor cell behaviour, showing that oligodendrocyte progenitor cells (OPCs) exist in the mature brain, where they produce new myelinating oligodendrocytes throughout life. In more recent years, she has been examining the signals that direct OPC behaviour and working to understand how myelin plasticity regulates brain function.
Read more about Associate Profess Kaylene Young here.