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Medical Research Seminar: Using gut microbial metabolites to treat cardiovascular disease

November 2 @ 12:00 pm - 1:00 pm

A/Prof Francine Marques

Monash University

About the Talk:
Cardiovascular disease remains the main cause of death in Australia. A/Prof Marques’ research has pioneered the exciting concept that dietary fibre protects against cardiovascular disease by manipulating our gut microbiota. Moreover, she identified key metabolites called short-chain fatty acids (SCFAs) as involved in this protection. In her presentation, she will present evidence for the involvement of gut microbes in the setting of hypertension, how we could manipulate our gut microbes to lower prevalence of cardiovascular disease and the mechanisms involved. To achieve this ambitious vision, she integrates pre-clinical (animal) and clinical studies, leveraging her expertise in genomics, molecular biology and physiology.

About the Speaker:
Associate Professor Francine Marques is a National Heart Foundation Future Leader Fellow and head of the Hypertension Research laboratory at Monash University. She has published 87 papers in peer-reviewed journals including Nature Reviews Cardiology, Circulation, Nature Medicine and Hypertension. She has secured $4.2 million in competitive grant funding including as lead chief investigator from the NHMRC and the Heart Foundation. Her team investigates the molecular mechanisms behind the development of hypertension, with focus on disease identification and prevention via the gut microbiota using both animal and clinical trials. Associate Professor Marques is an elected member of the executive committee for the High Blood Pressure Research Council of Australia (HBPRCA), the chair of the mentoring committee for the International Society of Hypertension, the inaugural chair of the Emerging Leaders Committee of the Australian Cardiovascular Alliance, and an elected member of the steering committee for the Gordon Research Conference on Angiotensin. She won 25 awards including the prestigious 2019 American Heart Association Hypertension Council Goldblatt Award, the 2020 Young Tall Poppy Science Award, 2020 HBPRCA and 2021 ISH Mid-Career Award, and 2021 Australian Academy of Science Gottschalk Medal, and was a finalist for the 2019 Eureka Emerging Leader in Science Prize.
Read more about A/Prof Francine Marques’ work here.



November 2
12:00 pm - 1:00 pm
Event Category:


Online meeting