In a comprehensive analysis of human gene activation data, researchers from the Centenary Institute have discovered that the dipeptidyl peptidase-4 (DPP4) gene family is strongly implicated in the development of human hepatocellular carcinoma (HCC), the most common type of primary liver cancer.
Research from the Centenary Institute has found that a new dual drug approach could offer up a highly effective treatment strategy for melanoma, the most serious form of skin cancer responsible for more than 1,700 deaths each year in Australia.
Associate Professor Anthony Don, Head of the Lipid Metabolism and Neurochemistry Laboratory at the Centenary Institute has received a funding grant of $115,000 from MS Research Australia to help investigate and develop drugs that can better treat multiple sclerosis (MS).
World-leading research into sudden cardiac death (SCD) in young people and multiple sclerosis has been boosted with two Centenary Institute researchers successfully securing prestigious NHMRC Ideas Grants.
Research led by the Centenary Institute, the University of Technology Sydney and the University of Queensland has shown for the first time a link between chronic obstructive pulmonary disease (COPD), an often fatal lung condition, and the gut microbiome.
Australian scientists, including from the Centenary Institute, have found that humans, and most likely the entire animal kingdom, share important genetic mechanisms with a jelly-like sea sponge.
A ground-breaking discovery by Centenary Institute scientists has provided new understanding as to the nature of proteins and how they exist and operate in the human body.
Researchers at the Centenary Institute have found that sensitivity of the immune system to ‘good’ gut bacteria is present in zebrafish, proving that the ability of an animal to benefit from good gut bugs is evolutionarily conserved whether you walk or swim.
Centenary Institute researchers have discovered that genetic testing can identify ‘concealed cardiomyopathies’ in nearly a quarter of sudden cardiac arrest (SCA) survivors who seem to have a normal heart.
Research led by the Centenary Institute has discovered that the lack of an enzyme in the liver called sphingosine kinase 2 (SphK2) results in pronounced insulin resistance and glucose intolerance, both symptoms of early stage type 2 diabetes.