Agnes Ginges Centre for Molecular Cardiology
Our research is about saving lives because we know that many cardiovascular conditions are caused by underlying genetic faults. We look to improve diagnosis and management of patients and families. Currently, we are seeing a reduction in sudden cardiac death from genetic heart diseases.
Our research is focused on understanding the clinical and genetic basis of inherited heart disease. We use a range of approaches including human gene discovery studies, basic cellular systems, animal models of human disease, and population-based psychosocial and public health studies.
Our research involves state-of-the-art approaches including whole exome sequencing, mRNA and microRNA profiling, and RNASeq. Most importantly, we have the key clinical resources, including well phenotyped individual patients and families, which form the basis of all our genetic studies.
To get to this point, we have developed cohorts and national registries of patients and families with inherited heart diseases. We also utilise the latest in genetic technology in order to form the basis of our novel gene discovery studies.
Finding a Cure
Around 30,000 Australians die every year from sudden cardiac death. Around four young Australians, under the age of 35, die every week from sudden cardiac death.
We know that there are around 40 cardiovascular conditions caused by underlying genetic faults. We all have around 22,000 genes, but a fault in just one can result in a life threatening heart condition.
We can already see our research directly reducing sudden cardiac death in our communities. Our new gene discoveries are being used as improved diagnostic tools, we are rolling out implantable cardioverter defibrillator therapy and we are actively involved in improving public health measures.
YOUTUBE VIDEOS
Our research is focused on understanding the clinical and genetic basis of inherited heart disease. We use a range of approaches including human gene discovery studies, basic cellular systems, animal models of human disease, and population-based psychosocial and public health studies.
Our research involves state-of-the-art approaches including whole exome sequencing, mRNA and microRNA profiling, and RNASeq. Most importantly, we have the key clinical resources, including well phenotyped individual patients and families, which form the basis of all our genetic studies.
To get to this point, we have developed cohorts and national registries of patients and families with inherited heart diseases. We also utilise the latest in genetic technology in order to form the basis of our novel gene discovery studies.
Finding a Cure
Around 30,000 Australians die every year from sudden cardiac death. Around four young Australians, under the age of 35, die every week from sudden cardiac death.
We know that there are around 40 cardiovascular conditions caused by underlying genetic faults. We all have around 22,000 genes, but a fault in just one can result in a life threatening heart condition.
We can already see our research directly reducing sudden cardiac death in our communities. Our new gene discoveries are being used as improved diagnostic tools, we are rolling out implantable cardioverter defibrillator therapy and we are actively involved in improving public health measures.
YOUTUBE VIDEOS
