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Centenary Institute - Medical Research

International Day of Women and Girls in Science

Meet Associate Professor Jodie Ingles

Jodie Ingles wears many hats. She is a cardiac genetic counsellor, an award-winning scientist, a widely-published researcher, an Associate Professor, as well as a wife and a mum.

All this, and she’s only 38 years old!

This International Day of Women and Girls in Science, we recognise Jodie for her brilliant breakthroughs in genetic heart research, and for paving the way for female scientists trying to balance life as a researcher with motherhood.


Growing up

Jodie grew up in a small town in country New South Wales, where at the time, only a handful of her high school cohort would go on to study at university. She wasn’t quite sure what she wanted to do, but she loved the idea of science and medicine. Jodie also read books about Ebola and enjoyed the Jurassic Park book series, which she says went into a lot of detail about mathematic and genetic engineering.

“I used to think there was no way a country girl could make this a career. I never had a career plan. I just followed the path that made me happy, and eventually ended up where I am.”

Jodie admits she didn’t know a lot about women in science growing up, but says she was lucky to grow up in a supportive and encouraging environment at home.

“My dad would always buy me books about how things work. When I was considering studying medicine, he called one of the universities and had them post all their information to us.”


Scientific achievements

Jodie went on to complete a Bachelor of Biomedical Science, a Master of Public Health, a Graduate Diploma in Genetic Counselling and a PhD. Most recently, she was promoted to Associate Professor in the Faculty of Medicine and Health at the University of Sydney.

Since 2003, Jodie has been working at the Centenary Institute in Professor Chris Semsarian’s (AM) Molecular Cardiology Program. Her role involves seeing families in the clinic as a cardiac genetic counsellor and overseeing the return of genetic testing results.

As part of her PhD, Jodie co-established the Australian Genetic Heart Disease Registry in 2008, and in 2015, she became Head of the Clinical Cardiac Genetics group at Centenary.

“I do what I do, because for 15 years, I’ve been lucky to meet so many amazing families in our clinics and I want to find answers for them. We are there for families when they’re at absolute rock bottom, and being able to help them through that is our goal.”

Jodie has been the recipient of many prestigious awards and grants, including:

  • NHMRC Career Development Fellowship, Level 1
  • NSW Cardiovascular Research Network Rising Star Ministerial Award
  • Heart Foundation Future Leader Fellowship
  • NSW Health EMCR Fellowship, Cardiovascular Health
  • Rita and Cornforth Medal for PhD Achievement, University of Sydney
  • Peter Bancroft Prize for Research Work, Sydney Medical School
  • CSANZ Affiliate’s Prize

In 2018, Jodie also delivered the prestigious plenary Janus Lecture at the American National Society of Genetic Counselors (NSGC) annual conference in Atlanta, Georgia (US). The conference was attended by about 2,500 genetic counsellors from all around the world.


Balancing academic life with being a mum

On top of being a highly-successful young scientist, Jodie is also a mum. She had her almost 10-year-old son during her PhD and admits while it can be difficult, having a family means she has to make it work.

“Centenary has a great attitude towards working mums. I’m a total workaholic, so I am sure I would burn out very quickly without being forced to leave the office by 4PM. It’s impossible to stress about a grant or research paper being rejected when you have this amazing little human who wants to tell you about his soccer game.”

Jodie says it can become particularly tricky when she’s required to travel overseas for conferences, which usually happens at least five times a year. She believes it’s important to surround yourself with supportive people, saying she’s particularly grateful for her father-in-law who helps her husband look after her son when she’s away.

Her advice to women who are considering having children but also want to progress their career?

“Just do it. There is never a right time, you just find a way. However, I would add that there is only so much time in a day so if you are looking after small children, then you probably need to be realistic about how much work you can achieve.”


Importance of having a mentor

Jodie is adamant it would be almost impossible to succeed in academia without a mentor, because there is no way of being able to see the big picture, and how the little steps along the way lead to something important later on.

“I was lucky to find a great mentor in Professor Chris Semsarian who was able to help guide me in building a track record that is now competitive in the fellowship and grant schemes. Without being able to attract funding, we have no ability to work towards independence.”

Associate Professor Jodie Ingles, Professor Chris Semsarian, cardiac research, heart research, medical research

And now, Jodie is finding joy in helping to create opportunities for junior staff and students.

“Being able to pull people up with you is so important. It’s the only way I’ve been able to succeed and I intend on creating those opportunities for as many people as I can.”


Gender equity in science

Statistics show that while women make-up more than half of science PhD and early career researchers, they account for just 17 per cent of senior academics in Australian universities and research institutes.[1]

As winner of the Centenary Institute’s 2017 Bank of Queensland Gender Equity Award, Jodie is one of those looking to change those figures.

Jodie believes the tide is already turning, with more public recognition of gender issues in the academic sector. However, she also thinks there is much room for improvement.

“It can be easy to blame any rejection on the fact I am female. I think that wondering how it is impacting on how people perceive me and my applications isn’t overly helpful. I would really like to see how blinding of applications would go, like the NHMRC.”

Jodie was also selected as a mentee in the 2018 Franklin Women’s six-month mentoring program, alongside fellow Centenary researcher Dr Jessamy Tiffen.


Advice to girls looking to pursue a career in science

Jodie offers the same advice to anyone looking to enter the world of science, regardless of their gender.

“Science is a career for people who are curious, hard-working, creative and determined. Applying those skills in medical research offers the potential to have a positive impact on many people.”

Looking back on her own career to date, she also believes it’s crucial to be confident in what you do.

“I wish I had believed more in myself. I haven’t had a typical career path and at some level, I still feel like the country girl who needs to always prove herself. That can be exhausting! I’m trying to better accept those insecurities as who I am, but I think it’s important they don’t hold you back.”


About International Day of Women and Girls in Science

  • International Day of Women and Girls in Science is held on 11 February every year.
  • It came out of a resolution adopted by the United Nations General Assembly in December 2015, which established an annual International Day to recognise the critical role women and girls play in science and technology communities.
  • The Day is designed to raise awareness about the significant gender gap which has persisted in all levels of science, technology, engineering and mathematics. Women remain underrepresented in these fields.

Read the media release as a PDF.

To arrange an interview with Associate Professor Jodie Ingles or to request images, please contact: Centenary Institute Media and Communications Manager, Laura Parr, l.parr@centenary.org.au, 02 9565 6108

[1] Gender Equity, Australian Academy of Sciencehttps://www.science.org.au/supporting-science/gender-equity

New insights into why young people die suddenly

A study led by scientists at the Centenary Institute could provide some families with a clearer insight into why a young loved one may have experienced an otherwise unexplained cardiac arrest and in some cases, sudden death.

Arrhythmic right ventricular cardiomyopathy (ARVC) is a poorly understood genetic cardiomyopathy. It occurs if the muscle tissue in the right side of the heart undergoes cell death and is replaced with fat and scar tissue; disrupting the heart’s electrical signals and causing an abnormal heart rhythm.

Researchers from the Centenary Institute, Royal Prince Alfred Hospital, Royal North Shore Hospital and the University of Sydney examined four families in which one family member (under the age of 30 years) had ARVC and experienced a cardiac arrest as a result. In two cases, the patients survived, while in the other two cases, the patients died suddenly.

Studies to date suggest patients must exhibit an obvious structural change to their heart before they are at risk of a sudden cardiac episode. This study shows for the first time that this isn’t always the case, with none of the four patients’ hearts exhibiting any structural changes. In all four cases however, a genetic error in a particular gene called PKP2 was identified.

“This study could force us to re-evaluate how we treat patients with this particular type of cardiomyopathy. For example, should we be more aggressive in treating these patients who carry the PKP2 gene error, but don’t show any clinical evidence of having this disease?” says Head of Centenary’s Molecular Cardiology Program, Professor Chris Semsarian AM.

“It also opens the door for potential gene-targeted therapy further down the track, with the aim of preventing patients with ARVC from experiencing a cardiac arrest.”

Lead author and Head of Centenary’s Clinical Cardiac Genetics Group within the Molecular Cardiology Program, Dr Jodie Ingles says the results may also help to provide closure for some families.

“In many cases of cardiac arrest or sudden death, it can be difficult to identify the precise cause, particularly if the patient’s heart does not show any structural changes. Now, we can attribute a specific gene as to why some people die suddenly, in cases that would otherwise go unexplained,” says Dr Ingles.

View the full media release as a PDF.

Read the paper published in Circulation: Genomic and Precision Medicine.

Learn more about Centenary’s other life-saving medical research breakthroughs.

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