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New platform to evolve proteins for better therapies

Researchers from the Centenary Institute, in collaboration with the University of Sydney, have developed a powerful new tool to evolve proteins directly within mammalian cells, offering a more effective way to design medical treatments tailored to the human body.

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Event shines spotlight on genetic heart disease in young people

The Centenary Institute has hosted a community event aimed to advance understanding of inherited heart disease and sudden cardiac death in young people.

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Turning off protein may help prevent liver cancer

New research from the Centenary Institute has found that switching off a specific protein in liver cells may help prevent the early development of liver cancer.

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New mRNA vaccine boosts immunity against TB

A study into the new vaccine’s effectiveness, published in eBioMedicine, was led by experts from the Sydney Infectious Diseases Institute at University of Sydney, the Centenary Institute and the Monash Institute of Pharmaceutical Science (MIPS) at Monash University.

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    Dr Charles Bailey
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News and Events

  • New platform to evolve proteins for better therapies

    Researchers from the Centenary Institute, in collaboration with the University of Sydney, have developed a powerful new tool to evolve proteins directly within mammalian cells, offering a more effective way to design medical treatments tailored to the human body.
    News Type: Media release
    Date 08 May 2025
  • Turning off protein may help prevent liver cancer

    New research from the Centenary Institute has found that switching off a specific protein in liver cells may help prevent the early development of liver cancer.
    News Type: Media release
    Date 16 Apr 2025
  • Event shines spotlight on genetic heart disease in young people

    The Centenary Institute has hosted a community event, titled ‘A Needle in a Haystack: Unlocking the Secrets of Genetic Heart Conditions’. The event aimed to advance understanding of inherited heart disease and sudden cardiac death in young people.
    News Type: Community
    Date 10 Apr 2025
  • Finding answers for sudden cardiac death in young people

    Each week in Australia, up to three young people die suddenly and unexpectedly from sudden cardiac death, often due to an undiagnosed genetic heart condition. These conditions typically go unnoticed until tragedy strikes, leaving families devastated and searching for answers.
    News Type: Media release
    Date 02 Apr 2025
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Microscope Monday! This image submitted by Philip Microscope Monday!

This image submitted by Philip Tong in our 2012 Scientific Image Prize is entitled 'Scaffolds in Biology'. 

This three-dimensional rendered imaging is of elastin in the ex-vivo human dermal skin using multi-photon microscopy.

Elastin is highly visible because of its auto-fluorescent structure and hence can be imaged without the need for staining. It is an essential part of many tissues in the body such as the skin, lung and blood vessels and allow them to return to their normal shape after stretching or contracting.

#centenaryinstitute #medicalresearch #elastin
We love sharing our research with the community. We love sharing our research with the community.

We believe that community engagement and health advocacy has a key role in our quest to understand diseases and find cures.

We want to stay abreast of current and emerging concerns amongst patients and to be more effective in communicating the progress we are making.

To learn more and to become involved with our community engagement programs, go to 'Community and Research' link in bio.

#centenaryinstitute #medicalresearch #community #CommunityEngagement
Microscope Monday! This image entitled 'www.brain Microscope Monday!

This image entitled 'www.brain.org' was submitted by Saparna Pai in our 2013 Scientific Image competition.

Like the world wide web, this tile scan of the brain shows venules (blue), arterioles (red) and capillaries forming a complex network – pathogens are like internet viruses that disrupt the network (pink) and immune cells are like anti-virus (green) that detect them. 

The image was captured using a Leica SP5 Confocal Microscope.

#CentenaryInstitute #MedicalResearch #brain #scientificimage
Researchers from the Centenary Institute, in colla Researchers from the Centenary Institute, in collaboration with the University of Sydney, have developed a powerful new tool to evolve proteins directly within mammalian cells, offering a more effective way to design medical treatments tailored to the human body.

Published in the prestigious journal Nature Communications, the study reports on the development of PROTEUS (PROTein Evolution Using Selection), a cutting-edge platform that enables directed evolution.

Join first author Dr Alex Cole commented: “By bringing directed evolution into mammalian cells, PROTEUS is opening the door to developing new therapies that are more effective and designed to function where they’re needed, in the human body.”

The researchers believe that PROTEUS could help drive future advances in gene therapy, disease research and next-generation medical treatments.

Learn more at link in bio.

#CentenaryInstitute #MedicalResearch #PROTEUS #cells
Microscope Monday! This image entitled 'Tumour Ne Microscope Monday!

This image entitled 'Tumour Nest' was an entry from Research Officer David Hill in our 2012 Scientific Image competition.

This multi-photon microscopy image shows red and green melanoma cells surrounded by, and invading, blue and white connective tissue in the skin.

#CentenaryInstitute #MedicalResearch #melanoma #scientificimage
We are seeking a talented Events & Consumer Engage We are seeking a talented Events & Consumer Engagement Lead to deepen our engagement with our stakeholders, supporters and consumers. 

This role will develop a creative, informative and entertaining program of events, in addition to leading the establishment of a recruitment and engagement program for health consumers to interact with Centenary researchers. 

To learn more about this role and to apply go to 'Centenary Institute Careers' link in bio.

#CentenaryInstitute #MedicalResearch #events #ConsumerEngagement
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We acknowledge the Gadigal of the Eora Nation, the traditional custodians of the Country on which the Centenary Institute stands.

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