Made by cells for cells: harnessing extracellular vesicles for a healthier and sustainable future

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About the talk: Traditional medicine has only taken us so far in promoting tissue regeneration. Extracellular vesicles (EVs) – cell-drived membranous nano-structures – have been hailed as the next generation in regenerative medicine. EVs ferry hundreds of bioactive molecules such as proteins, lipids and RNAs to synergistically influence the behaviour of multiple target cells in a fashion that far surpasses existing human inventions. Harnessing the multifunctionality of EVs will revolutionise the way we regenerate tissues damaged by injury or disease. Here, we present the potential of EVs to treat lung injuries and enable safe, effective, and functional tissue regeneration, which will pave the way for a healthier and sustainable future.

Speaker

  • Professor Wojciech Chrzanowski

    The University of Sydney

    Professor Wojciech Chrzanowski is Head of Nano-medicine and Nano-Bio-Characterisation laboratory in the Faculty of Medicine and Health. He is a biomedical engineer who translates the science of nanoparticles and bio-characterisation at nanoscale to human applications. His work addresses a desperate need for effective nanotechnologies that regulate cells to promote desired tissue repair…

    Professor Wojciech Chrzanowski is Head of Nano-medicine and Nano-Bio-Characterisation laboratory in the Faculty of Medicine and Health. He is a biomedical engineer who translates the science of nanoparticles and bio-characterisation at nanoscale to human applications. His work addresses a desperate need for effective nanotechnologies that regulate cells to promote desired tissue repair. Wojciech laboratory pioneers the use of nanoscale characterisation techniques to understand interactions of nanoparticles with biological systems. To this end he develops solutions to determine the safety of nano-materials by measuring their effects in different environments. From these he learns to design less harmful nano-materials to keep people and the environment safe. Wojciech‘s contribution to the field is exemplified by over 200 peer-reviewed publications, six patents and over 70 invited talks and seminars. He is a recipient of 16 prizes and awards for his work including 2019 Barry Inglis Medal from National Measurement Institute, 2018 Vice Chancellor’s Award for Excellence in Research and Education and 2018 Outstanding Paper Award from Royal Society of Chemistry. His proven ability to lead a translational research program to fruitful completion was recognised by his award of a place in the 2019 SPARK Accelerating Australia program to commercialise his team’s aerosol device for EV delivery to lungs. In addition to academia, he successfully established research programs with industry, and he leads a research program of nano technology for non-invasive medicine. In addition, he co-leads an Australian arm of Horizon2020 international program Shaping Innovative Products for Sustainable Tissue Engineering Strategies – SHIFT.

    Professor Wojciech Chrzanowski