Impact
Since our beginning over forty years ago, the Centenary Institute has generated scientific knowledge that has deepened understanding of complex disease, driven new diagnostics and therapies, and strengthened global health.
Discoveries that change lives
Across cancer, cardiovascular disease, rare disorders, liver disease, infectious diseases and immunology, our researchers have produced landmark discoveries that have delivered real-world benefits for patients, families and communities.
Our impact is reflected in major research achievements that have helped shape modern medicine and health.
These include world-first insights into immune tolerance that underpin today’s autoimmune and cancer therapies; the Cellular Calculus, which transformed vaccine development and design; discoveries that guided the creation of modern diabetes drugs; and breakthroughs in gene therapy delivery that aim to make treatments safer and more effective.
We have also transformed the investigation of sudden cardiac death; played a pivotal role in advancing tuberculosis vaccines and control strategies; uncovered mechanisms driving liver disease; and created new tools that could dramatically improve how cancer treatment responses are assessed.
All of these discoveries reflect the Centenary Institute’s enduring commitment to curiosity, collaboration and scientific excellence and the profound impact that dedicated research can have on human health.

Discovery drives modern cancer and autoimmune therapies
How world-first insights into immune tolerance that underpin today’s autoimmune and cancer therapies. Read more

A major breakthrough for gene therapy paves the way for better treatments
How a new gateway into human cells could dramatically improve safety, effectiveness, and accessibility. Read more

‘Cellular Calculus’ ‘transforms vaccine development and design
How understanding cell division and a mathematical formula influenced vaccine development and design. Read more

Unveiling an unknown enzyme
How a lifetime of dedication has led to a new understanding of liver disease, diabetes and potential cancer treatments. Read more

Transforming the landscape of cardiac care
How a determination to save lives resulted in new procedures and provided families with answers. Read more

A compound that could help combat cancer
A fast, new way to assess the efficacy of cancer treatment could prolong lives. Read more

