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    Centenary Institute > People > Professor Mark Gorrell

Professor Mark Gorrell

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  • Gorrell

Email Email m.gorrell@centenary.org.au

Professor Mark Gorrell heads the Liver Enzymes in Metabolism and Inflammation Program. He trained in cell biology, virology, immunology and protein biochemistry at the Australian National University and University of Melbourne in Australia, and at Johns Hopkins University in the USA.

His research is focussed upon liver scarring and cancer prevention and treatment, chronic liver disease pathogenesis, diabetes, protein and enzyme biochemistry and cell biology related to the proteases DPP4, DPP9 and fibroblast activation protein (FAP).

He has authored over 184 publications attracting H index 55, and > 11,000 citations. His research was important in the development of DPP4-targeted therapies for type 2 diabetes, which are now used to treat millions of patients. His research experience also includes protein biochemistry, small RNA viruses, transcriptomics, proteomics and cell biology.

Professor Gorrell has supervised more than 21 PhD and M Phil students. He is active in the International Proteolysis Society, the Gastroenterological Society of Australia, NHMRC grant reviews, and is an editorial board member for Cancers and for Scientific Reports.

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  • Cancer Innovations

    Cancer Innovations

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  • Chronic diseases ,

Publications

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For access to all Publications via Pub Med.

News

  • New FAP-Index could transform early detection of severe liver disease

    Researchers from the Centenary Institute have developed a new diagnostic tool, the FAP-Index, that could significantly improve how doctors identify people at risk of serious liver damage caused by metabolic fatty liver disease. The condition affects around one in three Australians with cases projected to increase by 25% to over 7 million by 2030.
    Date 20 Feb 2026
  • Prestigious editorial award for Professor Gorrell

    Professor Mark Gorrell from the Centenary Institute’s Centre for Cancer Innovations has been awarded a Springer Nature Editorial Contribution Award celebrating his outstanding editorial work for the highly respected journal Scientific Reports. The award recognises editorial board members who have made a notable contribution to the journal’s peer-review and publishing processes. Professor Gorrell has served ...
    Date 16 Jun 2025
  • Turning off protein may help prevent liver cancer

    New research from the Centenary Institute has found that switching off a specific protein in liver cells may help prevent the early development of liver cancer.
    Date 16 Apr 2025
  • DPP9 deficit linked to immune disorders in children

    Researchers, including from the Centenary Institute, have reported that ultra-low levels of the dipeptidyl peptidase 9 (DPP9) enzyme could be contributing to immune disorders in children.
    Date 04 Oct 2022
  • DPP9 enzyme role in cancer revealed

    A new study from German and Centenary Institute researchers has provided new understanding of an enzyme called dipeptidyl peptidase 9 (DPP9) and its role in cancer development.
    Date 04 Aug 2022
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