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Inflammation Fact Sheet

Think you know about inflammation? Think again. Redness, swelling, muscle aches…that’s not even the half of it. Chronic inflammation is a key driver of diseases, such as cancer, cardiovascular disease and autoimmune diseases. Read more.

Cellular Inflammation: The Secret Killer

We now know that inflammation plays a crucial role in our immune system however research has shown that it plays a role at a cellular level in the development of disease.

We concentrate our research on inflammation mechanism. It underlies a number of prevalent acute and chronic conditions, as well it drives the initiation and progression of cancer and cardiovascular disease.

Inflammation research: why it matters

Diabetes

A third of all diabetics will suffer from vision loss and potential blindness during their lifetime. This condition is caused by inflammation in the retina blood vessels.

Centenary’s Impact 

We have developed an exciting new drug which has the potential to mend the damaged blood vessels and prevent loss of sight.

Read more about our diabetes work here.

Alzheimer’s Disease

Alzheimer’s disease is the leading cause of dementia and the second leading cause of death in Australia. Evidence is mounting that inflammation plays a key role.

Centenary’s Impact 

We are investigating new ways to target and treat debilitating diseases such as Alzheimer’s disease, by focusing our research on inflammation in the brain.

Read more about our Alzheimer’s disease work here.

Respiratory Diseases

Two of the top five killers of Australians are diseases of the lungs and airways. Inflammation appears to play a major role.

Centenary’s Impact 

We are identifying new ways to tackle inflammation by developing comprehensive ‘molecular maps’ for Chronic Obstructive Pulmonary Disease, lung cancer and asthma. 

Read more about our Asthma work here.

Inflammation Research Foundation – Cellular Inflammation: The Secret Killer (Article).

Metaflammation

Metaflammation is a new term that refers to low levels of inflammation throughout the body.

Your body use the essential repair process of inflammation to heal the body. When you have a full blown infection your levels are very high. Metaflammation is different. It is much much lower but constant.

This new aspect of inflammation has come to light, its connection with chronic metabolic diseases, like obesity and diabetes. One of the reasons this link is really important is that we are able to control with small molecule or biological therapeutics some aspects of inflammation. This approach might become really useful in treating some diseases that were thought to be diet or environment influenced and may become a devastating problem in the future.

Inflammation research: why it matters

Diabetes

A third of all diabetics will suffer from vision loss and potential blindness during their lifetime. This condition is caused by inflammation in the retina blood vessels.

Centenary’s Impact 

We have developed an exciting new drug which has the potential to mend the damaged blood vessels and prevent loss of sight.

Read more about our diabetes work here.

Centenary Institute scientists are working on many aspects of inflammation, including metaflammation. For more details on our research approaches see here.

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