The Centenary Institute has collaborated with fellow medical research institute, the Hudson Institute in Victoria, to develop a novel model system for accurately monitoring tumour stage and immune cells involvement.
Head of Centenary’s Liver Enzymes in Metabolism and Inflammation Program, Professor Mark Gorrell, was involved in the research project.
Ovarian cancer develops slowly and the immune system is crucial in controlling the tumour. In this particular study, the researchers modified ovarian cancer cells so they glowed in a way that can be seen in live laboratory mice models – enabling counts of tumour cells and immune cell subsets when each tumour is removed.
This system has allowed the researchers to learn new information on tumour growth, as well as discover which immune cells are in the tumour.
The researchers plan to apply the model to other cancers, including liver cancer.
A collaborative project between the University of Sydney and the Centenary Institute to find a COVID-19 vaccine has been featured on 10 News.
Centenary Institute researchers have discovered novel insights into the molecular factors controlling vital regulators of the innate immune response system.
Professor Phil Hansbro has been interviewed by Prime7 News on his new study that will be focused on exploring the health impacts of people’s exposure to bushfire smoke.