It takes two to tango: effect of calcium on iron levels

Centenary Institute


Research led by Centenary Institute scientists has developed a new framework for understanding how iron is transported around the body, making leeway for the development of more targeted therapies for people suffering from iron-related chronic health conditions, such as anaemia.

In a study published in the prestigious scientific journal Nature Communications, a group of international scientists, including three from Centenary, determined that the presence of calcium is required for iron to be transported into the blood stream, and that iron potentially is transported in complex with a metabolite through ferroportin.

“Our findings suggest there could be a relationship between low blood calcium and anaemia. This advances our understanding of how dietary iron is absorbed into the bloodstream, which may aid in the development of strategies to manipulate ferroportin through therapeutics or drugs,” says lead author Dr Chandrika Deshpande from Centenary’s Structural Biology Program.

Read the full media release.

View the research article in Nature Communications.

Learn more about the work of Centenary’s Structural Biology Program.

Latest News

Aspirin to fight an expensive glo…

Centenary Institute Research Breakthrough

Our Immune-Vascular Interactions Laboratory’s Dr Elinor Hortle and Dr Stefan Oehlers have found a brand new target for treating drug-resistant tuberculosis.

Antioxidants help contain killer …

Tuberculosis Research - Centenary Institute

Research by Centenary’s Dr Stefan Oehlers in collaboration with the University of Sydney has identified a powerful tool to fight tuberculosis.

Centenary scientists recognised f…

Cancer Council NSW awards funding to innovative cancer research projects including Centenary’s Professor Phil Hansbro and Dr Justin Wong.


News Topics