New information on potential therapeutic target for cancer
Centenary Institute researchers in the Molecular Hepatology Laboratory have uncovered new information about an enzyme called DPP9 that they believe to be a potential therapeutic target for limiting tumour growth and its ability to spread to and in the liver.
Centenary’s researchers have shown that the DPP9 enzyme can regulate human liver cancer cell growth and movement. In addition, they have bred mice that lack DPP9 and shown that newborn mice need the enzyme to survive, highlighting its importance.
This latest research was conducted by three PhD students, Yiqian Chen, Emma [Hui] Zhang and Margaret Gall.