Johansen Lab
The Johansen Lab seeks to understand the mechanisms involved in respiratory infections to develop more effective therapies.
The Johansen laboratory seeks to investigate how bacterial infections like Tuberculosis (TB) and Non-Tuberculous Mycobacteria (NTM), and viral infections like COVID-19 and Influenza, interact with the host immune response and cause disease outcomes. By furthering our understanding of what happens and why, this will help us to develop tailored therapies that can fight these infections.
We are also exploring how risk factors like sex, age and underlying chronic respiratory disease can lead to worsened outcomes, and finding ways that allow us to overcome these risk factors to provide improved outcomes for patients.
Centre for Infectious Diseases & Immunity
- Bacterial and viral infections
- Respiratory diseases
- Preclinical animal models
- Host-pathogen interactions
- Respiratory immunology
- SARS-CoV-2 infection of 3D in vitro cardiac spheroids models the activation of antiviral, inflammatory, fibrotic, and contractile responses in a dose-dependent manner
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The ESX-4 substrates, EsxU and EsxT, modulate Mycobacterium abscessus fitness
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Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus
People
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Dr Matt Johansen
Lab Head, Chancellor’s Research Fellow & Lecturer
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Ms Guanshu Zhao
Research Assistant -
Mr Tsung-Yu Pai
PhD Student -
Mr Raphael Nasr
PhD Student
