McCaughan
Liver diseases are caused by chronic inflammation. They are driven by many factors including viruses, autoimmune processes, genetic diseases and toxins such as alcohol.
We initially used human liver samples to screen for molecules that we up regulated. Since then we have taken some of these molecules and manipulated them in experimental models. This has allowed us to test whether these molecules actually play a role in causing liver injury.
According to The Australian Liver Association, liver disease now affects over six million Australians and has an annual cost burden of $50.7 billion.
Liver disease is responsible for one quarter of all organ transplants and if left untreated, results in liver cancer – our fastest growing form of cancer in Australia.
The increasing prevalence of all forms of liver disease, but in particular fatty liver disease with concurrent diabetes, is a huge burden. Our research stems from test tubes, to animal models, human models and clinical trials.
According to The Australian Liver Association, liver disease now affects over six million Australians and has an annual cost burden of $50.7 billion.
Liver disease is responsible for one quarter of all organ transplants and if left untreated, results in liver cancer – our fastest growing form of cancer in Australia.
The increasing prevalence of all forms of liver disease, but in particular fatty liver disease with concurrent diabetes, is a huge burden. Our research stems from test tubes, to animal models, human models and clinical trials.
