Dr Roediger was awarded his PhD in 2011 and is currently Head of the Skin Inflammation Group within Professor Wolfgang Weninger’s Immune Imaging Laboratory at the Centenary Institute. Here, Dr Roediger combines cutting-edge technology with sophisticated mouse models to visualise and functionally characterise immune cells in vivo.
Contributions to Research: Dr Roediger is an acknowledged expert in cutaneous immunology, having co-authored 13 primary papers and 6 reviews on the topic, 3 as corresponding or co- corresponding author. He is also recognized for his expertise in a number of cytometric and imaging technologies, particularly multiphoton microscopy. Dr Roediger’s contribution to research include the first ever characterisation of dermal dendritic cells by multiphoton microscopy (Ng et al. PLoS Pathog 2008) and the discovery of patrolling neutrophils in the skin (Ng et al. J Invest Dermatol 2011).
More recently, he was instrumental in the discovery of two hitherto undescribed immune populations in the skin: a novel population of skin-resident TCR gamma-delta T cells (Sumaria et al. J. Exp Med. 2011) and a unique population of CD103+ group 2 innate lymphoid cells (ILC2; Roediger et al. Nat. Immunol. 2013). In this work, he provided the first ever identification skin ILC2 and demonstrated that uncontrolled activation and expansion of these cells is sufficient to induce inflammatory skin disease. Dr Roediger was also involved in the first ever visualisation of the innate immune response to Staphylococcus aureus infection in vivo, which identified a hitherto unrecognised role for perivascular macrophages in neutrophil recruitment (Abtin et al. Nat. Immunol. 2014).
Dr Roediger’s contributions to research are evidenced by his 21 original articles (14 in the last 5 years), the majority of which are in leading international journals, including Nature Immunology, The Journal of Experimental Medicine, Proceedings of the National Academy of Sciences of the USA, Journal of Investigative Dermatology and Journal of Immunology.