Scientists at Centenary have uncovered a new pathway in the body which fights cancer; paving the way for the development of drugs that improve the prognosis of patients with melanoma and other types of cancer.
“Sadly, Australia has one of the highest rate of melanoma in the world, with more than 1800 Australians dying from the disease each year. Our research has improved our understanding of how the body mounts the anti-cancer immune response but has also opened up ways scientists can develop new therapies to target this cell type in melanoma,” says Stuart Cook of Centenary’s Skin Imaging and Inflammation laboratory, the lead author on the paper.
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Professor John Rasko AO has led a world-first clinical trial into engineered stem cell treatment use, treating 15 patients with steroid resistant acute graft-versus-host disease.
Centenary Institute research has discovered that the lack of an enzyme in the liver called sphingosine kinase 2 results in pronounced insulin resistance and glucose intolerance, both symptoms of early stage type 2 diabetes.
Research led by the Centenary Institute has shown that a healthy weight and coffee consumption may help lower the risk of high-risk drinkers developing alcohol-induced cirrhosis.