The talk, delivered during the Cardiovascular Inflammation session, featured a recent discovery of a new mechanism that controls movement of immune cells during inflammation.
“Cardiovascular diseases are the leading cause of death worldwide with inflammation underlying the development of coronary heart disease and heart attack,” said Dr Chiu.
“Abnormal recruitment of immune cells to the blood vessel linings can cause inflammation leading to obstruction of blood vessels.”
“Using a cross-disciplinary approach, I discussed how the movement of immune cells are controlled by force and chemical reactions. This force-chemical mechanism can be targeted to potentially alleviate inflammation and help treat diseases,” Dr Chiu said.
Dr Chiu’s talk was titled, ‘Mechano-redox control of Mac-1 de-adhesion by protein disulphide isomerase’.