Skip to content
Home page - Centenary Institute Centenary Institute

Primary menu

  • Research
        • Research

          The latest medical research into our most complex health challenges across cancer, cardiovascular disease and inflammation

          Learn more

        • Cancer
        • Inflammation
        • Cardiovascular
        • Programs
        • Laboratories
        • Diseases
        • Expertises
        • Services and instrumentation
  • Support us
        • Support us

          By supporting the Centenary Institute you can help improve human health through excellence in medical research

          Learn more

        • Workplace giving
        • Host or join a fundraiser
        • Gift in your Will
        • Donate in Memory
  • Impact
        • Impact

          Our research develops new diagnostics, treatments and cures for some of the most deadly and debilitating diseases affecting society today

          Learn more

        • Breakthroughs
        • Community and research
        • Real stories
  • Health hub
        • Health hub

          A range of practical information to assist in the possible preventions to disease through evidence-based research on how the body works.

          Learn more

        • Inflammation
        • The Good Gut Anti-Inflammatory Diet
        • Ageing
        • Exercise Snack Program
  • News & events
        • News & Events

          Explore the latest research breakthroughs and ways you can take part in our series of digital and in-person events

        • News
        • Events
        • Media Hub
  • About us
        • About us

          We are world-leading independent medical research institute that drives collaboration to accelerate and translate solutions to our most complex health challenges

          Learn more

        • Governance
        • Corporate information
        • Annual reports
        • Our researchers
        • Careers and studies
        • Contact
  • Donate
    Centenary Institute > News > Pre-clinical models crucial for effective COVID-19 treatments

Pre-clinical models crucial for effective COVID-19 treatments

Date time 20 August, 2020
News Type News type Research News
Centenary Institute researchers have outlined the crucial importance of diverse animal, cell and tissue model usage in the development of effective COVID-19 treatments and medications.

Centenary Institute researchers have outlined the crucial importance of diverse animal, cell and tissue model usage in the development of effective COVID-19 treatments and medications.

In a review publication published in the prestigious journal ‘Mucosal Immunology’, the paper authors noted that the scientific and clinical community was racing to define and develop effective preventions and treatments. However, that these efforts were being hampered by  competing interests, small scale programs and a lack of defined patient cohorts and defined readouts.

“What is needed now is head-to-head comparison of existing drugs, testing of safety including in the background of predisposing chronic diseases, and the development of new and targeted preventions and treatments,” said Professor Phil Hansbro, Director of the Centenary UTS Centre for Inflammation and senior author of the publication.

“This is most efficiently achieved using representative animal models of primary infection including in the background of chronic disease with validation of findings in primary human cells and tissues,” he said.

“Interrogation of representative models lets us define cause and effect and to explain mechanisms of pathogenesis that are then able to be confirmed and translated in human studies,” said Centenary Institute researcher Dr Matt Johansen, the review paper’s lead author.

The paper can be accessed here.

More information on the Centenary UTS Centre for Inflammation can be found here.

Themes

  • Inflammation

    Inflammation

Media enquires

For all media and interview enquiries, please contact Tony Crawshaw, Media and Communications Manager

Phone number Phone Number 0402 770 403

Email Email t.crawshaw@centenary.org.au

Recent Stories

  • Meet Dr Bobby Boumelhem

    Dr Bobby Boumelhem, a dedicated researcher at the Centenary Institute, is on a mission to enhance the quality of life for individuals grappling with liver disease. Diseases such as hepatitis, liver cancer, non-alcoholic fatty liver disease and cirrhosis pose significant health challenges.
    News Type: Profiles
    Date 22 Sep 2023
  • Cancer drug for COVID-19

    Researchers, including Dr Matt Johansen from the Centenary UTS Centre for Inflammation and Professor Phil Hansbro, Director of the Centenary UTS Centre for Inflammation, have discovered that a cancer drug could play an important role in limiting the damaging effects of lung disease in COVID-19 patients.
    News Type: Research News
    Date 19 Sep 2023
  • Centenary Institute supports the Voice

    As a medical research institute deeply committed to improving the health outcomes of all Australians, the Centenary Institute wholeheartedly endorses the principles of voice, treaty, and truth, and gives its full support to the Voice to Parliament.
    News Type: Institute
    Date 11 Sep 2023
  • Link between gut bacteria and long-term COVID-19 effects revealed

    Researchers, including from the Centenary Institute, have highlighted a potential link between gut microbiota (the collection of bacteria residing in the digestive system) and enduring health problems experienced by individuals who have recovered from COVID-19.
    News Type: Research News
    Date 07 Sep 2023

Subscribe to receive news on
research updates and free events

Newsletter

The Centenary Institute is a world-leading independent Medical Research Institute.

We acknowledge the Gadigal of the Eora Nation, the traditional custodians of the Country on which the Centenary Institute stands.

About

  • About
  • Governance
  • Corporate information

Research

  • Programs
  • Our researchers
  • News
  • Media hub

Careers & studies

  • Career opportunities
  • Life at Centenary

Links

  • Contact
  • Privacy statement

Contact us

Building 93, Royal Prince Alfred Hospital
Missenden Rd
Camperdown NSW 2050 Australia
Telephone +61 2 9565 6100
Fax +61 2 9565 6101

Contact Privacy

Centenary Institute ABN 22 654 201 090 (DGR 1) • Centenary Institute Medical Research Foundation ABN 85 778 244 012 (DGR 2)
© 2017 Centenary Institute of Cancer Medicine and Cell Biology.

  • Linkedin
  • Facebook
  • Twitter
  • Youtube
  • Instagram