Topics: Infectious diseases

Ever wondered what it’s like to be a scientist?

Hi, I’m Elinor and I’m post-doctorate researcher at Centenary.

Centenary Institute researchers have uncovered new insight into Mycobacterium abscessus, a highly drug-resistant bacteria that can cause serious infection and lung damage in vulnerable people. The bacteria is considered an emerging health threat with infection numbers on the rise globally.

The Centre of Research Excellence in Tuberculosis Control (TB-CRE) has held a seminar at the Centenary Institute in support of World TB Day, 24 March 2022. TB, primarily affecting the lungs, is one of the world’s deadliest infectious killers. Every day, over 4,100 people die from TB world-wide and nearly 30,000 people fall ill with ...

Centenary Institute research has revealed new insight into tackling mycobacterial infections which are responsible for chronic diseases that include tuberculosis (TB), leprosy and serious skin ulcerations.

Dr Elinor Hortle, medical researcher at the Centenary Institute has been interviewed on Sydney radio 2GB’s Healthy Living program, discussing her latest findings on tackling mycobacterial infections. Responsible for diseases that include tuberculosis (TB), leprosy and serious skin ulcerations, mycobacterial infections cause significant harm and mortality to human health. Approximately 1.5 million people die each ...

Hi, I’m Phil Hansbro and I’m Deputy Director at the Centenary Institute as well as Director of the Centenary UTS Centre for Inflammation.

Hi, I’m Patrick and I Head the Liver Immunology Program at Centenary.

Hi, I’m Dr Claudio Counoupas and I research tuberculosis at Centenary.

The Centenary Institute has hosted the annual symposium of the Centre of Research Excellence in Tuberculosis Control (TB-CRE), bringing together over 130 specialists in tuberculosis (TB).

Originally from Canada, Dr Dan Hesselson, Head of the Centenary Institute’s Directed Evolution Laboratory, has a true passion for ice hockey, a sport he played regularly as a child and one which he still plays recreationally now.

The Centenary Institute and the University of Sydney, together with collaborators, have been awarded an AU$19 million contract from the National Institute of Allergy and Infectious Diseases, part of the US National Institutes of Health (NIH), to develop the next generation of tuberculosis (TB) vaccines.

Centenary Institute and University of Sydney PhD student, Lina Daniel, is lead author on a newly published paper that has found that Mycobacterium tuberculosis remodels the architecture of the lymph nodes – limiting the immune system’s ability to overcome tuberculosis (TB) infection.

Researchers from the Centenary Institute and the University of Sydney have developed a new nasal vaccination strategy that induces potent lung immunity and protection against the SARS-CoV-2 coronavirus.

Jasmine Nguyen has been awarded the high honour of an early-offer University of Sydney International Scholarship, to pursue her COVID-19 and lung disease research, in a PhD at the Centenary Institute.

Research led by the Centenary Institute and the University of Sydney – focused on the development of a new nasal COVID-19 vaccine – has received close to $1m in grant funding from the NSW COVID-19 Vaccine Acceleration Research Grants Program.

The Centre of Research Excellence in Tuberculosis Control (TB-CRE) has held its annual symposium at the Centenary Institute, showcasing key tuberculosis (TB) research outcomes and bringing over 250 scientists together to enable TB discussion and facilitate future planning.

Researchers, including from the Centenary Institute, have highlighted a potential link between gut microbiota (the collection of bacteria residing in the digestive system) and enduring health problems experienced by individuals who have recovered from COVID-19.

A study by the Centenary Institute has revealed how a new mucosal (nasal delivered) vaccine can provide early protection against tuberculosis (TB) by drawing a particular type of immune cell into the lungs.

Researchers from the Centenary Institute and the University of Sydney have made a major discovery in vaccine science, gaining new insights into delta inulin as a crucial vaccine component. Their findings offer a promising pathway for advancing the next generation of vaccines.

Centenary Institute researchers have secured more than $2m in collective funding from the Federal Government in the latest round of National Health and Medical Research Council (NHMRC) Ideas Grants.

Medical researchers at the Centenary Institute have focused their efforts to understand how the coronavirus is causing COVID-19 and are launching projects that will investigate a range of potential treatment strategies.

A group of leading Australian researchers have uncovered a unique blood-based biomarker signature in individuals infected by tuberculosis (TB).

Centenary Institute researchers have examined the critical role of human enzymes and the coronavirus in a newly published scientific review article that explores potential strategies for COVID-19 disease treatment and management.

Research led by the Centenary Institute has discovered that immune cells accumulating within the tumour environment, called tumour-resident T cells, are a critical determinant in survival rates of patients suffering from throat cancer.

Australian researchers, including from the Centenary Institute have been awarded funding for a major project that aims to eliminate both active and latent tuberculosis (TB) found on Kiribati, an island nation in the central Pacific Ocean. The project will also support multidrug-resistant TB control education and management through the Pacific region.

Sydney researchers are taking an innovative approach to designing potential COVID-19 vaccines Ð using a tuberculosis vaccine to deliver components of the SARS-CoV-2 virus. Early results from pre-clinical testing in mice are promising.

A collaborative project between the University of Sydney and the Centenary Institute to find a COVID-19 vaccine has been featured on 10 News.

The Centenary InstituteÕs Executive Director, Professor Mathew Vadas, together with other leading Australian researchers, have featured in a recent ABC News article, explaining that COVID-19 appears to be far more than just a respiratory disease.

Centenary Institute researcher Dr Claudio Counoupas has featured as a case study in a 2020 AAMRI (Association of Australian Medical Research Institutes) Budget Submission to Federal Government.

Centenary Institute researchers have outlined the crucial importance of diverse animal, cell and tissue model usage in the development of effective COVID-19 treatments and medications.

The first case of COVID-19 reinfection has been documented by scientists from Hong Kong who report that a 33 year old man has been infected by two different strains of the virus. The second infection occurred more than four months after recovery from the first episode of the disease.

Research from the Centenary Institute has found that the human enzyme dipeptidyl peptidase (DPP4) does not bind to the spike protein of the SARS-CoV-2 virus and so cannot enable COVID-19 infection in our bodies.

The first study of human gene associations with severe COVID-19 has just been accepted for publication in the highly prestigious journal ÔNatureÕ.

Scientists in Australia have developed a method for the rapid synthesis of safe vaccines, an approach that can be used to test vaccine strategies against novel pandemic pathogens such as SARS-CoV-2, the virus that causes COVID-19.Ê

A team of Australian researchers, including from the Centenary Institute, has shown in a new study that older people and men tend to have higher levels of the enzyme ACE2 on the cells of their lower lungs - and that this may be the reason for their increased risk from COVID-19.

A collaborative project involving the University of Sydney, the Centenary Institute, the University of Technology Sydney and the Kirby Institute at UNSW Sydney, has received funding from the Medical Research Future Fund (MRFF) to continue work on the development of a unique, single-shot vaccine against COVID-19 variants of concern.

The Centenary Institute has hosted the TB-CRE 2021 Symposium, which has showcased the latest tuberculosis research from international members and collaborators, and provided a platform for TB discussion and planning.

The Centenary Institute has held its inaugural ‘Inflammation Symposium’ on 13 and 14 July, highlighting the latest in medical research across the field of inflammation and disease.

The Centenary Institute is pleased to note its involvement in, and support of, the newly announced NSW RNA Production and Research Network involving the stateÕs leading universities and other prominent health and medical research organisations.

Dr Matt Johansen from the Centenary UTS Centre for Inflammation has been interviewed by Carl Smith, journalist from the ABC Science Show.

Researchers from the Centenary UTS Centre for Inflammation and collaborators have been awarded a seed grant of $20,000 to advance a new treatment strategy for chronic obstructive pulmonary disease (COPD) patients suffering from influenza.

Dr Matt Johansen from the Centenary UTS Centre for Inflammation is the successful recipient of the Kenyon Foundation Inflammation Award for 2021.

New research by the Centenary Institute suggests that commonly prescribed anticoagulants – medicines, such as aspirin, that help prevent blood clots – may make urinary tract infections (UTIs) more severe.