Themes: Cancer Innovations

Dr Tiffen and Dr Tong shared practical knowledge about melanoma of the skin and provided insights into how medical research is improving outcomes for melanoma patients. Preventing and protecting yourself and your loved ones from melanoma should be a life-long commitment, but you cannot do it alone. This is why the Centenary Institute wants to ...

We have partnered with the Royal Botanic Garden Sydney and Australian Museum in celebration of science and National Science Week

Centenary’s Inclusion Gender Equity Program (IGEP) brings an entertaining and exciting half-day event

About the talk: INPP4B suppresses PI3K/AKT signalling by converting PI(3,4)P 2 to PI(3)P and we recently demonstrated INPP4B facilitates class PI3Kα crosstalk with Wnt signalling in ER+ve breast cancer on late endosomes. We observed in these studies that the conversion ofPI(3,4)P 2 to PI(3)P on late endosomes by INPP4B, was associated an increase in the ...

The Centenary Institute will host an Exhibition at Parliament House Sydney showcasing images taken by our scientists as part of their research endeavours that have both scientific significance and are visual masterpieces!  The Scientific Image Prize is an annual internal competition designed to recognise the incredible research of Centenary’s scientists, as well as their artistic ...

Ever wondered what it’s like to be a scientist?

Ageing represents one of the greatest medical, social and economic challenges – in Australia and globally.

Hi, I'm Katrina and I'm in charge of Translation and Commercialisation at Centenary.

Hi, I'm Nick and I'm the Chief Operating Officer at Centenary.

Hi I’m Dr Ulf Schmitz and I lead the Computational BioMedicine Research Laboratory at Centenary.

Focus, accuracy and persistence–these are just some of the many qualities possessed by Julie Feng, a researcher in the Centenary Institute’s Gene and Stem Cell Therapy Program and also a world-leading kendo practitioner.

Hi, I’m Patrick and I Head the Liver Immunology Program at Centenary.

Hi, I’m Mark and I’m Head of the Liver Enzymes in Metabolism and Inflammation Program at Centenary.

Hi, I’m A/Prof Devanshi Seth and I head Centenary’s Alcoholic Liver Disease Laboratory. 

Dr Jessamy Tiffen has been promoted to the Scientific Faculty at the Centenary Institute where she will be a part of the senior science leadership team.

Researchers have discovered a new way to treat hepatocellular carcinoma (HCC), the most common type of liver cancer and the third leading cause of cancer death worldwide.

The Centenary Institute has received important funding from the RT Hall Trust to bolster two ground-breaking cancer research initiatives. Almost one in two Australians will be diagnosed with cancer by the age of 85. Cancer is a leading cause of death, claiming around 50,000 Australians annually.

Associate Professor Guy Lyons, a Laboratory Head at the Centenary Institute’s Centre for Cancer Innovations, has been awarded the prestigious Barry Preston Award by the Matrix Biology Society of Australia & New Zealand.

New research from the Centenary Institute and the University of Sydney has uncovered important insights into the immune environment within liver cancer, the sixth most common cancer worldwide and the third leading cause of cancer-related deaths.

Dr Mark Schreuder, a researcher at the Centenary Institute’s Centre for Cancer Innovations, has received the Kenyon Foundation Inflammation Award for 2024.

Dr Jessamy Tiffen, Head of the Centre for Cancer Innovations at the Centenary Institute, and her master’s student Laura Nicholls, have been awarded a $10,000 research grant from the Australian Melanoma Research Foundation.

Research conducted by the Centenary Institute has revealed a promising new approach to tackling melanoma, an aggressive form of skin cancer notorious for its resistance to conventional treatments.

The Centenary Institute has received vital grant funding from Cancer Australia to lead new research efforts targeting chemotherapy resistance in ovarian cancer patients.

Three Centenary Institute scientists have been awarded grants totalling $150,000 from the Tour de Cure cancer research funding scheme.

Research conducted at the Centenary Institute has given rise to a ground-breaking tool called 'Invasion-Block' that can identify drugs capable of halting the spread of cancer cells. The pioneering development could lead to better treatments for melanoma, the most dangerous form of skin cancer.

Hi, I’m Kristina and my job is to ensure that our high-tech state-of-the-art microscopes at Centenary are operating well and that all staff, including students, know how to use them correctly for their research.

Dr Jessamy Tiffen, Head of the Centenary Institute’s Epigenetics of Melanoma Program, has been an invited panel guest at a special leadership event hosted by the law firm Jones Day.

Research conducted at the Centenary Institute has unveiled crucial insights into the underlying molecular mechanisms of breast cancer. The findings could lead to a more effective treatment for the disease, which claims the lives of over 3,000 Australian women and men annually.

You may have wondered what makes stem cells so important and why they are needed for medical research.

Dr Dannel Yeo from the Centenary Institute and Clinical Associate Professor Kate Mahon from Chris O’Brien Lifehouse, have been awarded an inaugural Sydney Cancer Partners Translational Fellowship.

The Centenary Institute has given members of the public, school students and stakeholders the opportunity to find out what it’s like to be a scientist – and to better understand what it takes to be at the cutting-edge of medical discovery – with its unique ‘speed dating’ event, held as part of the Spark Festival.

The Centenary Institute has engaged with kids and the wider community as the Research Partner of Sydney Science Trail held at the Botanic Gardens and Australian Museum in celebration of National Science Week.

The Centenary Institute’s Ms Aster Pijning has been awarded the 2021 Thompson Prize by the Australian Society for Biochemistry and Molecular Biology.

A new study from German and Centenary Institute researchers has provided new understanding of an enzyme called dipeptidyl peptidase 9 (DPP9) and its role in cancer development.

Dr Ulf Schmitz, Head of the Centenary InstituteÕs Computational BioMedicine Laboratory has been recognised as an outstanding investigator in the field of cancer research, being awarded an NHMRC Investigator Grant.

Improving the clinical care of patients with cirrhosis will be the focus of a new three year PhD project being undertaken at the Centenary Institute, Sydney.

A ground-breaking discovery by Centenary Institute scientists has provided new understanding as to the nature of proteins and how they exist and operate in the human body.

CentenaryÕs Summer Research Scholarship program for 2020/21 is now open and accepting applications!

The Future Leader Fellowship at the Centenary Institute has been jointly awarded to two outstanding researchers for 2020ÐDr Jessamy Tiffen (left) from the InstituteÕs Melanoma Oncology and Immunology Program and Dr Shweta Tikoo (right) from the InstituteÕs Immune Imaging Program.Ê

Centenary Institute scientists have discovered that genes on the X chromosome may be key to the improved survival rates of females with melanoma-as compared to their male counterparts.

New research from the Centenary Institute has provided novel insights into the role of these spacer DNA or introns in the development and function of monocytes and macrophages, essential components of the innate immune system.

Centenary Institute PhD candidate Ms Aster Pijning has won the jury's vote for first prize as well as the people's choice prize for her efforts at the Sydney Catalyst Perfect Pitch Competition.

Research led by the Centenary Institute has discovered that immune cells accumulating within the tumour environment, called tumour-resident T cells, are a critical determinant in survival rates of patients suffering from throat cancer.

Dr Annalicia Vaughan from the Centenary UTS Centre for Inflammation is the successful recipient of the Kenyon Foundation Inflammation Award for 2022.

Scientists at the Centenary Institute have reported a new strategy to battle melanoma, the most dangerous form of skin cancer, responsible for approximately 1,700 deaths in Australia each year.

The Centenary InstituteÕs Dr Stefan Oehlers (Immune-vascular Interactions Laboratory within the Tuberculosis Research Program), Dr Jessamy Tiffen (Melanoma Oncology and Immunology Program) and Dr Hui Emma Zhang (Liver Enzymes in Metabolism and Inflammation Program) have all been named on the EducatorÕs list of Higher Education Rising Stars for 2020.

Cancer Council NSW has awarded funding to 14 ground-breaking cancer research projects including three to the Centenary Institute.

Dr Jessamy Tiffen from the Centenary InstituteÕs Melanoma Immunology and Oncology Program has participated in a special ÔWomen in EducationÕ event held at Pymble Ladies College, Sydney.

Some of our leading cancer researchers, Professor Phil Hansbro, ProfessorÊPeter Hersey, Dr Mainthan Palendira and DrÊJessamy Tiffen have presented their project updates and recent findings to consumers and supporters at our recent consumer engagement session.

Scientists from the Centenary Institute have developed a new therapeutic strategy that could potentially help the fight against advanced-stage melanoma.

Jodie Ingles wears many hats. She is a cardiac genetic counsellor, an award-winning scientist, a widely-published researcher, an Associate Professor, as well as a wife and a mum.

Research from the Centenary Institute has found that a new dual drug approach could offer up a highly effective treatment strategy for melanoma, the most serious form of skin cancer responsible for more than 1,700 deaths each year in Australia.

World-leading research into pancreatic cancer has been boosted with the Centenary Institute’s Professor John Rasko AO awarded a $100,000 ‘Innovation in Early Detection’ grant from The Australian Pancreatic Cancer Foundation. One of the deadliest forms of cancer, the five-year survival rate for pancreatic cancer is less than 12% in Australia. A reason for the low ...

The Centenary Institute’s Dr Madeleine Gill has today received a National Health and Medical Research Council (NHMRC) postgraduate scholarships grant to continue her research into understanding unexplained heart failure in patients with liver cirrhosis. Cirrhotic cardiomyopathy affects approximately 50 per cent of patients with cirrhosis and can be a barrier to liver transplantation and is ...

Professor Philip Hogg, Head, ACRF Centenary Cancer Research Centre, has featured on Nine News explaining his new theranostics research, recently funded by the Cancer Institute NSW. A form of personalised cancer treatment for the patient, the term ‘theranostics’ refers to a combined therapy and diagnostics approach where tumour markers are employed to deliver a therapeutic isotope ...

Two Centenary Institute scientists have been awarded grants totalling $4.3 million from the Cancer Institute NSW to undertake critical cancer related medical research.

The Centenary Institute has announced it will establish a new precision medicine laboratory, enabling world-leading research into the use of theranostics to treat cancer, thanks to a grant from the Australian Cancer Research Foundation (ACRF).

The Centenary InstituteÕs Summer Research Scholarship Program for undergraduate students has drawn to a close with 14 Êstudents undertaking a series of Ôrapid-fireÕ style presentations to staff, explaining their completed research projects and talking about their work-related experiences at Centenary over the summer months.

Researchers from the Centenary Institute have developed a new approach to fighting melanomas that fail to respond – or are resistant – to standard treatments.

Aster Pijning, PhD candidate at the ACRF Centenary Cancer Research Centre, has had her science recognised with an image from her paper selected for the recent front cover of the prestigious journal ÔBloodÕ.

Research led by the Centenary Institute has found that a compound extracted from a commonly cultivated orchid could be a potential new treatment option for prostate cancer.

The Centenary Institute is pleased to note its involvement in, and support of, the newly announced NSW RNA Production and Research Network involving the stateÕs leading universities and other prominent health and medical research organisations.

Researchers from the Centenary Institute and the Royal Prince Alfred Hospital (RPAH) are co-investigators on three separate liver cancer focused projects that have recently received funding from the Australian GovernmentÕs Medical Research Future Fund (MRFF) and the Cancer Institute NSW.

Early career researchers from three of SydneyÕs leading medical research institutes, the Centenary Institute, the Heart Research Institute and the Woolcock Institute have come together to deliver the ÔECR Think Tank ProgramÕ for 2021.

World-class research into melanoma, the deadliest form of skin cancer, has been boosted with Dr Jessamy Tiffen, Head of the Centenary Institute's Melanoma Epigenetics Laboratory, receiving a $447,000 project grant from Cancer Council NSW.

In a comprehensive analysis of human gene activation data, researchers from the Centenary Institute have discovered that the dipeptidyl peptidase-4 (DPP4) gene family is strongly implicated in the development of human hepatocellular carcinoma (HCC), the most common type of primary liver cancer.